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Case Study of Pharmaceutical Ingredients Derived from Clay Minerals
Econ. Environ. Geol. 2015 Jun;48(3):221-9
Published online June 30, 2015
Copyright © 2015 Economic and Environmental Geology.

Su-Eon Jin, Jangik Ike Lee and Sung-Joo Hwang*

College of Pharmacy, Yonsei University
Received June 25, 2015; Accepted June 27, 2015.
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License ( which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Clay minerals have been used in pharmaceutical industries as active ingredients and excipients without pharmacological activity such as diluents, emulsifying agents, viscosity-increasing agents, and lubricants. For example, bentonite, kaolin, magnesium aluminum silicate, and talc are generally and extensively used pharmaceutical ingredients, which are restrictedly regulated by Pharmacopoeias. We discuss the physicochemical and biopharmaceutical properties of clay minerals. In addition, we introduce the cases of pharmaceutical applications of clay minerals. From this review, pharmaceutical applications of clay minerals can be one of strategies for the development of high valueadded products from clay minerals.
Keywords : clay minerals, pharmacy, pharmacopoeia, active ingredients, pharmaceutical excipients


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